As previously stated, many antioxidants are essential nutrients. Natural antioxidants, such as vitamins C and E, act synergistically. Antioxidants can be more effective if they come from a diet rich in fruits and vegetables. Nutritionists recommend eating 6 or more daily servings of antioxidant-rich fruits and vegetables. Everyone agrees that the use of antioxidant supplements to combat aging may be helpful, but there is no agreement on what should be the most effective doses .
Anti-aging medicine recognizes that stress of all kinds causes aging, but it has not yet developed individualized treatment. There are countless sources of internal and external stress and individual stress levels vary considerably. A neglected cause of internal stress is poor hydration. Water is essential for the proper functioning of many internal functions. Too much or too little water causes stress and aging. When you are older (over 80), the perception of thirst diminishes and dehydration can easily take hold. Antioxidants themselves are another source of neglected stress. High doses (or greater than certain amounts, but not specified) of additional antioxidants are a known cause of stress.
To be useful, antioxidant supplements must prevent other types of stress that stress that they create themselves. Knowing the correct dosages of supplements that can do this is an essential part of anti-aging treatment. A healthy young man in his twenties, well nourished, will have less internal stress than an older individual in his sixties. For a younger individual, lower amounts of antioxidants may be safer than higher amounts. A senior, whose many internal homeostatic mechanisms are less able to handle internal stress, may benefit more from a greater amount of antioxidants. Theoretically, an antioxidant-based anti-aging treatment will slow down the rate at which cell damage occurs. The cells will become "sick" more slowly. Over time, as fewer diseased cells are replaced at a slower rate, the number of cells retaining longer telomere chains will be higher. You can then reasonably expect this to translate into an increase in life expectancy. For now, the recommended but imprecise approach to reducing the rate of cell damage is to increase your daily consumption of antioxidant-rich fruits and vegetables, slightly increase your intake of antioxidants, and take various vitamins and small amounts of antioxidants. amounts of antioxidants. dietary supplements every day. One study showed that taking a good multivitamin supplement was associated with longer telomere length.
Ideally, the anti-aging treatment should be adapted to each individual. The key here would be to measure and minimize the cumulative effects of different types of stress on an individual basis. Practical, easily measurable biological markers for various types of stress do not exist yet or are not used. When they are used, it will be easy to customize the individual dosages of antioxidants so that everyone has "optimal" levels throughout his life. "Optimum" levels would maintain a safe reserve of protective antioxidants in the body.
Next, I will briefly discuss the most popular nutrients associated with anti-aging. The most popular antioxidants, vitamins and nutrients often associated with good health and anti-aging are: beta-carotene (vitamin A), vitamin C, vitamin E, various flavonoids, omega 3 and omega-6. , Co-enzyme Q10, lycopene, selenium.
There are dozens of supplements that are known to effectively treat the specific symptoms of old age. Some of the best known supplements include: DMAE, acetyl-l-carnitine, L-carnosine, alpha-lipoic acid, DHEA, L-arginine and melatonin.
Good food contains some of the previously mentioned antioxidants. Some other popular foods associated with anti-aging include: green tea, turmeric and red wine.
All of the above products have unique biological properties and, in my opinion, are "good" for you if they are taken in low or moderate amounts. Some (eg Vitamin C) may also be "good" for you in larger amounts. Various studies on each of them may conflict. You must carefully study each substance on your own, but researchers have already discovered that several nutrients are associated with longer than average lengths of telomeres. These include: green tea, omega-3, vitamins A, C, D and E.
Vitamin E has been associated with the lengthening of the anti-aging properties of telomeres.
Green tea contains many antioxidants, including vitamins C, E and flavenoids. Flavenoids form a large class of antioxidants (including catechins and quercetin) that has many anti-cancer, antihypercholesterolemic, antibacterial (helps to prevent tooth decay) and anti-inflammatory properties. The tea leaves are rich in polyphenols. Daily consumption of 3 cups or more of green tea has been associated with above average telomere length.
Omega-3s are long-chain, anti-inflammatory, essential polyunsaturated fatty acids that help prevent heart disease, stroke, memory loss, depression, arthritis, cataracts and cancer. Omega-3s slow telomere shortening; that is, they can protect against aging at the cellular level.
Vitamin C is an abundant, water-soluble internal antioxidant that protects cellular components against the formation of free radicals caused by pollution and cigarette smoke. Many studies have associated high intakes of vitamin C with lower rates of cancer of the mouth, larynx and esophagus. Vitamin C has shown promise in the treatment of premature aging and possibly even aging.
Due to the limited number of links that I can include in this article, I have not been able to provide more reference links in support of the previous paragraphs. If you are interested, send me an e-mail to the e-mail address indicated at the end of this article and I will send them to you.
The sooner you start an anti-aging treatment, the better it is, but it's never too late to start. All of the actual treatments will help you maintain an average telomere chain length above average.
The goal of the theory of programmed death of aging is to tackle the root causes of aging. This objective includes attempts to slow down or reverse the process of telomere shortening. Two of these treatments are: TA 65 and human genetic engineering.
TA 65 is a product activating telomerase produced and marketed by Sierra Sciences. The key ingredient of TA 65 is Astragalus, a plant extract known for its activation properties of telomerase. The product can work but I do not recommend it for several reasons. TA 65 is too expensive for an average person. A number of expensive health centers incorporate TA 65 into their programs. Again, these are financially out of the reach of the average person. Many have questioned the marketing tactics of Sierra Sciences and lawsuits are ongoing against TA 65.
The big problem I have with TA 65 is scientific honesty. The company made genetically modified mice that activated and activated telomerase at an early age. TA 65 was able to reactivate telomerase in these mice and allow them to lead a normal life. http://www.nature.com/news/2010/101128/full/news.2010.635.html
Using it to show the effectiveness of TA65 treatment is dishonest. This is not how telomerase normally works and there has been no real life extension beyond what it would have been without the genetic modification. In normal mice, the effects of TA65 were temporary and minimal or no prolongation of life was observed. http://www.thedailybeast.com/articles/2011/04/11/anti-aging-pill-new-study-on-ta-65-sparks-controversy.html
Human genetic engineering is the real solution to fight and conquer aging. It can directly tackle the root causes of aging. Progress in this area (eg CRISPR) allows for the insertion or removal of DNA base pairs at a specific point in our DNA. This means that the human genome can now be edited accurately if necessary. The life span of aged mice has been slightly increased by telomerase gene therapy. In humans, gene modification therapy has been frequently used for various medical problems. On September 15, 2015, Elizabeth Parrish was the first human to undergo anti-aging gene therapy. Anti-aging treatments will progress rapidly as our knowledge of the specifics of the human genome develops.
Current general sociopolitical attitudes seem to favor the development of research on aging. There is no recognized international political agenda to stop aging or prolong life, but since 2012, some pro-immortal political parties have emerged. Their goal is to support research on aging and prolongation of life, and to help provide access to advances in these areas for all. Among the many organizations supporting anti-aging research, the organization SENS (Strategies for Negligible Senescence) has developed an anti-aging research plan. They want to develop anti-aging therapies to repair most cell damage. SENS, is a charitable organization. Any anti-aging breakthrough resulting from the funding provided will become readily available to the public. In addition to the usual scientific research, the $ 1,000.00 Palo Alto Longevity Award is available to anyone who can offer effective anti-aging treatment.
As of 2015, all known anti-aging treatments are only partially effective. Depending on when you start a full anti-aging program, you can probably prolong your life from 10 to 25 years. Researchers at the Harvard School of Public Health have estimated that an anti-aging lifestyle can add 24.6 more productive years to lifespan. Knowledge about aging increases about 10 times every 10 years. This probably means that many of us have enough time to reap the benefits expected in the anti-aging research. A day soon, aging, like many other diseases, will be cured. While waiting for these anti-aging technological singularities to manifest themselves, the name of the game is to ensure that we stay healthy long enough to give back the benefits.